DeGregorio Family Foundation, 20th Anniversary
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2026 Michael F. Price Memorial Grant

The DeGregorio Family Foundation, in partnership with the Torrey Coast Foundation, is pleased to announce a Request for Applications (RFA) for up to $1 million regarding gastroesophageal cancer malignancies.

Request for Applications

The RFA is for high-impact projects up to $1 million. Projects evaluating novel targets, new approaches to validated targets, or new technology applied toward early detection and prevention are encouraged. The potential for patient impact will be prioritized. Completion should be within 1 to 3 years.

Funding: up to $1 million over 1 to 3 years, including indirect costs capped at 15%.

Eligibility

  • Applicants must be employed by a non-profit academic institution. Both U.S. and non-U.S. entities may apply.
  • No applications will be accepted from post-docs or individuals without a faculty appointment.
  • Interdisciplinary collaborations are encouraged, as are independent investigators at all career stages, especially those new to upper-GI cancers.
  • Proposals including a clinical trial require a clinical-trial budget and a commitment for the study drug.

Key Deadlines

  • September 4, 2026, 11:59 p.m. EDT: Letters of intent due (max 2 pages).
  • July 25, 2026: Applicants selected for full proposal notified.
  • September 4, 2026, 11:59 p.m. EDT: Full applications due.
  • November 2026: Winner(s) announced.

Questions should be sent in writing to sarah@degregorio.org and will be answered promptly. Applications are reviewed under the guidance of the Foundation’s Scientific Advisory Board, headed by Dr. Manish A. Shah.

Any publications or presentations resulting from this research must be acknowledged.

Instructions

All applicants are required to submit a letter of intent (no more than 2 pages, 11-point font, 0.75" margins) indicating the title, background, aims and abbreviated plan, impact, and institution(s) and key investigators involved. Please include a high-level budget and deliverables for each aim within the 2 pages.

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Only applicants who have been invited to apply may upload an application.

Due: September 4, 2026, 11:59 p.m. EDT

Full Grant Application

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Learn more about how the DeGregorio Family Foundation Turns Research into Action™

100% to research

100% of the DFF funds go directly to research.

Rigorous selection

The DFF Scientific Advisory Board looks for the best research that will attract follow-on funding.

Reporting & results

Grant recipients provide progress reports, publish papers, and attract follow-on funding to implement research.

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How our funds turn research into action.

100% of DFF funds go directly to research. Our Scientific Advisory Board selects the most promising early-stage science, work that attracts major follow-on funding and moves toward earlier diagnosis and better treatment.

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