Funds, Research, Action
How Our Funds Turn Research Into Action
54,000estimated new U.S. cases of stomach and esophageal cancer each year
27,000of those cases are terminal each year
2 of 3are not diagnosed until Stage 4
<1%of NIH cancer research funding goes to gastroesophageal cancer
Your Impact and Follow-On Funding
For every $1 donated, $10 is generated in follow-on funding, turning research into action.
- In 20 years, DFF has funded 38 grants for a total of just under $10 million.
- Those completed grants have received $60 million in follow-on funding.
- Eleven of those grants received follow-on funding from the NIH, where only approximately 5% of NIH applicants for gastroesophageal cancer research receive funding.
- One of the grants received the very prestigious Starr Foundation Grant for just under $1 million, a collaborative grant with Dana-Farber and MSKCC led by Dr. Shah.
What the DeGregorio Family Foundation Does
DFF is the only public foundation solely focused on funding research grants for gastric and esophageal cancer, also known as gastroesophageal cancer.
Early diagnosis is key. Stage 1 has a 48 to 78% survival rate. Unfortunately, symptoms arise around Stage 4, where the survival rate is around 6%.
DFF is dedicated to facilitating collaborative research on the pathogenesis, early diagnosis, and treatment of Upper GI Malignancies.
Turning Fact Into Fiction™
- 1100% of DFF funds go directly to research.
- 2The DeGregorio Family Foundation Scientific Advisory Board looks for the best research that will attract follow-on funding.
- 3Grant recipients provide progress reports and attract follow-on funding to implement their research.
- 4Doctors use research for early diagnosis and treatment.
At a Glance
Our Impact, Visualized
Two decades of funding, follow-on investment, and progress, all in one view.

Learn About the Grants We Have Funded
Thanks to donors like you. Every grant awarded since 2006.
More About Gastroesophageal Cancers
Facts, risk factors, and why early diagnosis matters so much.
